Re-thinking yellow fever vaccines: fighting old foes with new generation vaccines
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چکیده
منابع مشابه
Reactogenicity of Yellow Fever Vaccines in a and Collaborative Group for the Study of Yellow Fever Vaccines*
*The name of the Collaborative Group for the study of Yellow Fever vaccines is listed in the end of the article. Abstract Objective To compare the reactogenicity of three yellow fever (YF) vaccines from WHO-17D and Brazilian 17DD substrains (different seed-lots) and placebo. Methods The study involved 1,087 adults eligible for YF vaccine in Rio de Janeiro, Brazil. Vaccines produced by Bio-Mangu...
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Detailed analyses of the 5500 genes revealed by the complete Plasmodium genome sequence are yielding new candidate parasite antigens and strategies that may contribute to a successful vaccine against malaria in the coming decade.
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Since the 1980s, yellow fever has reemerged across Africa and in South America. The total of 18 735 yellow fever cases and 4522 deaths reported from 1987 to 1991 represents the greatest amount of yellow fever activity reported to the World Health Organization (WHO) for any 5-year period since 1948. There is an excellent vaccine against yellow fever. At present, a high proportion of travelers to...
متن کاملShortage of vaccines during a yellow fever outbreak in Guinea.
A yellow fever epidemic erupted in Guinea in September, 2000. From Sept 4, 2000, to Jan 7, 2001, 688 instances of the disease and 225 deaths were reported. The diagnosis was laboratory confirmed by IgM detection in more than 40 patients. A mass vaccination campaign was limited by insufficient international stocks. After the epidemic in Guinea, the International Coordinating Group on Vaccine Pro...
متن کاملThe phylogeny of yellow fever virus 17D vaccines.
In recent years the safety of the yellow fever live vaccine 17D came under scrutiny. The focus was on serious adverse events after vaccinations that resemble a wild type infection with yellow fever and whose reasons are still not known. Also the exact mechanism of attenuation of the vaccine remains unknown to this day. In this context, the standards of safety and surveillance in vaccine product...
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ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2021
ISSN: 2164-5515,2164-554X
DOI: 10.1080/21645515.2021.1895644